Ballyclare Rugby Club have been paired with Qualifying 2 leaders Omagh in the semi-finals of the Millar McCall Wylie Junior Cup.
The draw for the last four of the competition was made at Kingspan Stadium on Monday afternoon.
Ballyclare will be hoping to reach the final for the second year in a row as they host Omagh at The Cloughan.
The local side saw off Belfast Harlequins II 21-15 in Saturday’s quarter-final.
Instonians, who have enjoyed an unbeaten start to the season, will be strong favourites in their home clash against Enniskillen at Shaw’s Bridge.
The matches are to be played on or before Saturday, November 29.
Millar McCall Wylie Junior Cup semi-finals
Instonians v Enniskillen (Shaw’s Bridge)
Ballyclare v Omagh (The Cloughan)